POZ - Treatment News

Lipid Problems Explored in Women
Untreated HIV-infected women have lower levels of high-density lipoprotein cholesterol (HDL-C) and higher triglyceride levels compared with uninfected women, according to data from the Women's Interagency HIV Study. This pattern is aggravated by treatment that includes protease inhibitors.

May 25, 2007

'Serosorting' Risk can be High
A new mathematical model study suggests that, in some circumstances, serosorting may be associated with a higher risk of HIV infection, largely due to recently infected individuals still thinking and disclosing that they are seronegative.

May 23, 2007

Some Do Well After Treatment Interruption
Treatment interruption appears safe in a subgroup of HIV patients with preserved immune function, researchers report in the May 15th issue of the Journal of Infectious Diseases.

May 22, 2007

'Runaway' Theory Doesn't Explain Slow CD4 Loss
A new study refutes a longstanding theory of how HIV slowly depletes the body's capacity to fight infection.

May 18, 2007

HIV Vaccines May Work in Unexpected Ways
Even if current top HIV vaccine candidates do not prevent infection, they may still prove beneficial by prolonging disease-free survival and reducing secondary viral transmission.

Accurate Immune System Marker in Poor Countries
A new algorithm based on components of a complete blood cell count (CBC) gives a better estimate of CD4 cell count in HIV patients than estimates using the total lymphocyte count (TLC).

May 17, 2007

Regular Healthcare Visits a Key to Survival
HIV-positive people who do not consult with their healthcare providers on a regular basis do not live as long as those who do, according to a new study.

Spinal Chemicals May Predict HIV Dementia Risk
Various biomarkers indicate risk for development of HIV-associated dementia and for worsening of the condition, according to a report in the May 1st issue of Neurology.

May 16, 2007

Pubic Lipomas a Lipo Symptom?
A distinctive suprapubic fat pad is often present in patients with HIV-associated lipodystrophy, but it is often overlooked, Italian researchers report in the May 1st issue of the Journal of Acquired Immune Deficiency Syndrome.

May 15, 2007

Study Finds Abacavir Allergy Screening Useful
Hypersensitivity to abacavir can be detected by screening for HLA-B*5701 and is recommended for HIV-infected individuals who are candidates for the antiviral agent, French researchers report.

May 14, 2007

Kaletra Regimens 'Forgiving' of Missed Doses
Adherence rates to lopinavir/ritonavir regimens that fall below 95% can still bring about high rates of virologic suppression in HIV infection, according to a new study.

May 11, 2007

No Drop in Non-AIDS Cancer Rates
The effect of highly active antiretroviral therapy (HAART) on the incidence of non-AIDS-defining cancers in adults with AIDS is variable, with little effect seen in many instances, according to a report in the May 15th American Journal of Epidemiology.

May 10, 2007

PIs and Non-Nukes Cause Similar Metabolic Problems
The long-term metabolic consequences of antiretroviral therapy (ART) are similar with protease inhibitors (PI), nonnucleoside reverse transcriptase inhibitors (NNRTI), or the combination thereof, according to a report in the April 15th issue of the Journal of Acquired Immune Deficiency Syndromes.

May 08, 2007

Glitazones Not Likely Useful for Lipoatrophy
A Toronto-based study has concluded that “glitazones” don't offer any significant benefit compared to placebo in terms of reversing HIV-associated lipoatrophy.

Study Explores Lipid Problems in Women
New data indicate that lipid problems can vary, depending on a woman’s HIV status, whether or not she’s on HIV treatment, or which antiretrovirals she is using.

Hysterectomy Rates Higher in Women with HIV
Compared to seronegative at-risk women, those with HIV are more likely to undergo hysterectomy over a 5-year period. However, after adjustment, the difference does not reach significance.

May 04, 2007

Uncommon Causes of Stroke More Frequent in HIV
Atypical mechanisms of ischemic stroke are more common in HIV-infected patients than in the general population, according to a report in the April 17th issue of Neurology.

Green Tea for HIV Dementia
A compound derived from green tea greatly diminished the neurotoxicity of proteins secreted by HIV in a study involving mice suggesting a new approach to prevent and treat HIV-associated dementia.

May 03, 2007

HIV Treatment Good for Growth in Kids
HIV-infected children treated with highly active antiretroviral therapy (HAART) experience significant catch-up in height and weight, according to a report in the April issue of The Pediatric Infectious Disease Journal.

May 02, 2007

Race, Mental Health Affect HIV Treatment
Race and psychiatric disorders influence the risk of highly active antiretroviral therapy (HAART) failure, according to a report by researchers at Walter Reed Army Naval Medical Center, Washington, DC.

Possible Lipo Drug Dropkicks Glucose
A drug currently being studied as a lipodystrophy treatment may have an advantage of other compounds in development ? an ability to reduce blood glucose levels, a common problem in people with lipodystrophy.

May 01, 2007

PRO 140 Has Potent and Lasting HIV Effect
Progenics Pharmaceuticals has announced encouraging results from an early study of PRO 140, its experimental HIV entry inhibitor.

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